Citations
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Distinct skeletal stem cell types orchestrate long bone skeletogenesis.
Ambrosi TH, Sinha R, Steininger HM, Hoover MY, Murphy MP, Koepke LS, Wang Y, Lu WJ, Morri M, Neff NF, Weissman IL, Longaker MT, Chan CK.
Elife. 2021 Jul 19;10. pii: e66063. doi: 10.7554/eLife.66063
PMID: 34280086
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Group 2 innate lymphoid cells support hematopoietic recovery under stress conditions.
Sudo T, Motomura Y, Okuzaki D, Hasegawa T, Yokota T, Kikuta J, Ao T, Mizuno H, Matsui T, Motooka D, Yoshizawa R, Nagasawa T, Kanakura Y, Moro K, Ishii M.
J Exp Med. 2021 May 3;218(5). pii: e20200817. doi: 10.1084/jem.20200817
PMID: 33666647
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SLPI is a critical mediator that controls PTH-induced bone formation.
Morimoto A, Kikuta J, Nishikawa K, Sudo T, Uenaka M, Furuya M, Hasegawa T, Hashimoto K, Tsukazaki H, Seno S, Nakamura A, Okuzaki D, Sugihara F, Ninomiya A, Yoshimura T, Takao-Kawabata R, Matsuda H, Ishii M.
Nat Commun. 2021 Apr 9;12(1):2136. doi: 10.1038/s41467-021-22402-x
PMID: 33837198
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Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias.
Raundhal M, Ghosh S, Myers SA, Cuoco MS, Singer M, Carr SA, Waikar SS, Bonventre JV, Ritz J, Stone RM, Steensma DP, Regev A, Glimcher LH.
Nat Immunol. 2021 Apr;22(4):520-529. doi: 10.1038/s41590-021-00895-4
PMID: 33753942
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Conditional expression of HGAL leads to the development of diffuse large B-cell lymphoma in mice.
Raboso-Gallego J, Casado-García A, Jiang X, Isidro-Hernández M, Gentles AJ, Zhao S, Natkunam Y, Blanco O, Domínguez V, Pintado B, Alonso-López D, De Las Rivas J, Vicente-Dueñas C, Lossos IS, Sanchez-Garcia I.
Blood. 2021 Apr 1;137(13):1741-1753. doi: 10.1182/blood.2020004996
PMID: 33024996
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Oncogenic AURKA-enhanced N<sup>6</sup>-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q.
Cell Res. 2021 Mar;31(3):345-361. doi: 10.1038/s41422-020-00397-2
PMID: 32859993
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The neurotransmitter receptor Gabbr1 regulates proliferation and function of hematopoietic stem and progenitor cells.
Shao L, Elujoba-Bridenstine A, Zink KE, Sanchez LM, Cox BJ, Pollok KE, Sinn AL, Bailey BJ, Sims EC, Cooper SH, Broxmeyer HE, Pajcini KV, Tamplin OJ.
Blood. 2021 Feb 11;137(6):775-787. doi: 10.1182/blood.2019004415
PMID: 32881992
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A zebrafish model of granulin deficiency reveals essential roles in myeloid cell differentiation.
Campbell CA, Fursova O, Cheng X, Snella E, McCune A, Li L, Solchenberger B, Schmid B, Sahoo D, Morton M, Traver D, Espín-Palazón R.
Blood Adv. 2021 Feb 9;5(3):796-811. doi: 10.1182/bloodadvances.2020003096
PMID: 33560393
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E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates.
Wanet A, Bassal MA, Patel SB, Marchi F, Mariani SA, Ahmed N, Zhang H, Borchiellini M, Chen S, Zhang J, Di Ruscio A, Miyake K, Tsai M, Paranjape A, Park SY, Karasuyama H, Schroeder T, Dzierzak E, Galli SJ, Tenen DG, Welner RS.
Sci Immunol. 2021 Feb 5;6(56). pii: eaba0178. doi: 10.1126/sciimmunol.aba0178
PMID: 33547048
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SLFN11 promotes stalled fork degradation that underlies the phenotype in Fanconi anemia cells.
Okamoto Y, Abe M, Mu A, Tempaku Y, Rogers CB, Mochizuki AL, Katsuki Y, Kanemaki MT, Takaori-Kondo A, Sobeck A, Bielinsky AK, Takata M.
Blood. 2021 Jan 21;137(3):336-348. doi: 10.1182/blood.2019003782
PMID: 32735670
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Role of <i>HMOX1</i> Promoter Genetic Variants in Chemoresistance and Chemotherapy Induced Neutropenia in Children with Acute Lymphoblastic Leukemia.
Bukowska-Strakova K, Włodek J, Pitera E, Kozakowska M, Konturek-Cieśla A, Cieśla M, Gońka M, Nowak W, Wieczorek A, Pawińska-Wąsikowska K, Józkowicz A, Siedlar M.
Int J Mol Sci. 2021 Jan 20;22(3). pii: 988. doi: 10.3390/ijms22030988
PMID: 33498175
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The underestimated role of the microphthalmia-associated transcription factor (MiTF) in normal and pathological haematopoiesis.
Oppezzo A, Rosselli F.
Cell Biosci. 2021 Jan 13;11(1):18. doi: 10.1186/s13578-021-00529-0
PMID: 33441180
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Chromatin accessibility maps provide evidence of multilineage gene priming in hematopoietic stem cells.
Martin EW, Krietsch J, Reggiardo RE, Sousae R, Kim DH, Forsberg EC.
Epigenetics Chromatin. 2021 Jan 6;14(1):2. doi: 10.1186/s13072-020-00377-1
PMID: 33407811
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Lung megakaryocytes display distinct transcriptional and phenotypic properties.
Yeung AK, Villacorta-Martin C, Hon S, Rock JR, Murphy GJ.
Blood Adv. 2020 Dec 22;4(24):6204-6217. doi: 10.1182/bloodadvances.2020002843
PMID: 33351116
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Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells.
Zaro BW, Noh JJ, Mascetti VL, Demeter J, George B, Zukowska M, Gulati GS, Sinha R, Flynn RA, Banuelos A, Zhang A, Wilkinson AC, Jackson P, Weissman IL.
Elife. 2020 Nov 25;9. pii: e62210. doi: 10.7554/eLife.62210
PMID: 33236985
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Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner.
Bisht K, Tay J, Wellburn RN, McGirr C, Fleming W, Nowlan B, Barbier V, Winkler IG, Levesque JP.
Front Immunol. 2020;11:583550. doi: 10.3389/fimmu.2020.583550
PMID: 33123170
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Articular cartilage regeneration by activated skeletal stem cells.
Murphy MP, Koepke LS, Lopez MT, Tong X, Ambrosi TH, Gulati GS, Marecic O, Wang Y, Ransom RC, Hoover MY, Steininger H, Zhao L, Walkiewicz MP, Quarto N, Levi B, Wan DC, Weissman IL, Goodman SB, Yang F, Longaker MT, Chan CKF.
Nat Med. 2020 Oct;26(10):1583-1592. doi: 10.1038/s41591-020-1013-2
PMID: 32807933
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The Lysine Methyltransferase SMYD2 Is Required for Definite Hematopoietic Stem Cell Production in the Mouse Embryo.
Edwards MA, Brown MA, Alshiraihi I, Jarrell DK, Tucker HO.
Vet Sci. 2020 Jul 25;7(3). pii: E100. doi: 10.3390/vetsci7030100
PMID: 32722433
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Single-cell lineage tracing unveils a role for TCF15 in haematopoiesis.
Rodriguez-Fraticelli AE, Weinreb C, Wang SW, Migueles RP, Jankovic M, Usart M, Klein AM, Lowell S, Camargo FD.
Nature. 2020 Jul;583(7817):585-589. doi: 10.1038/s41586-020-2503-6
PMID: 32669716
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Geriatric fragility fractures are associated with a human skeletal stem cell defect.
Ambrosi TH, Goodnough LH, Steininger HM, Hoover MY, Kim E, Koepke LS, Marecic O, Zhao L, Seita J, Bishop JA, Gardner MJ, Chan CKF.
Aging Cell. 2020 Jul;19(7):e13164. doi: 10.1111/acel.13164
PMID: 32537886
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Calcium regulation of stem cells.
Snoeck HW.
EMBO Rep. 2020 Jun 4;21(6):e50028. doi: 10.15252/embr.202050028
PMID: 32419314
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Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate.
Pessoa Rodrigues C, Herman JS, Herquel B, Valsecchi CIK, Stehle T, Grün D, Akhtar A.
Sci Adv. 2020 May;6(21):eaaz4815. doi: 10.1126/sciadv.aaz4815
PMID: 32671208
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Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration.
Liu J, Hong J, Han H, Park J, Kim D, Park H, Ko M, Koh Y, Shin DY, Yoon SS.
Br J Cancer. 2020 May;122(10):1445-1452. doi: 10.1038/s41416-020-0788-8
PMID: 32203209
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Computational Approach to Identifying Universal Macrophage Biomarkers.
Dang D, Taheri S, Das S, Ghosh P, Prince LS, Sahoo D.
Front Physiol. 2020;11:275. doi: 10.3389/fphys.2020.00275
PMID: 32322218
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An in vivo genome-wide CRISPR screen identifies the RNA-binding protein Staufen2 as a key regulator of myeloid leukemia.
Bajaj J, Hamilton M, Shima Y, Chambers K, Spinler K, Van Nostrand EL, Yee BA, Blue SM, Chen M, Rizzeri D, Chuah C, Oehler VG, Broome HE, Sasik R, Scott-Browne J, Rao A, Yeo GW, Reya T.
Nat Cancer. 2020 Apr;1(4):410-422. doi: 10.1038/s43018-020-0054-2
PMID: 34109316